| 1 | Break My Heart | Rudimental | Columbia/SonyMusic | 210 | 2 |
| 2 | Strong | Romy And Fred Again.. | Young/BeggarsGroup/Rhythm | 208 | 2 |
| 3 | Dice | Lee Mvtthews feat. Rachel Leo | LeeMvtthews/AEI | 202 | 2 |
| 4 | Alone | Culture Shock And Gracie Van Brunt | CultureShock/TheOrchard | 196 | 2 |
| 5 | Crystal Eyes | Shapeshifter | A.R.T./Universal | 196 | 2 |
| 6 | Oh My | Luude And Issey Cross feat. Moby | SweatItOut/ADA/Warner | 192 | 2 |
| 7 | Rumble | Skrillex, Fred Again.. And Flowdan | OWSLA/Atlantic/Warner | 186 | 2 |
| 8 | Only You | K Motionz feat. Emily Makis | UKF | 176 | 2 |
| 9 | Work | Kevin McKay, Pupa Nas T And Denise Belfon | GlasgowUnderground | 168 | 1 |
| 10 | Mean It | Witters feat. LOVETA | Witters/TuneCore | 158 | 2 |
| 11 | Wings | Armand Van Helden | MOS/Universal | 158 | 2 |
| 12 | Hawt | TIBASKO | AnotherRhythm | 156 | 1 |
| 13 | Move Ya Body | Lance Savali | Mosaique/Universal | 154 | 2 |
| 14 | Lied To You | Andromedik And Luka | UKF | 148 | 2 |
| 15 | Spend It | Peking Duk feat. Circa Waves | SonyMusic | 144 | 2 |
| 16 | What You Say? | Young Marco | MOS/SonyMusic | 144 | 1 |
| 17 | Against The Tide | Delta Heavy And Lauren L'aimant | DeltaHeavy/AEI | 140 | 2 |
| 18 | Like The Old Days | Barry Can't Swim | Technicolour/NinjaTune/Border | 132 | 1 |
| 19 | Praise The Lord (Da Shine) (Durdenhauer Edit) | A$AP Rocky feat. Skepta | A$APWorldwide/SonyMusic | 128 | 2 |
| 20 | 6am | Channel Tres | ChannelTres/RCA/SonyMusic | 126 | 1 |
| 21 | Chasing Highs (Slow Motion) | James Hiraeth | Insanity/SonyMusic | 126 | 1 |
| 22 | Serotonin Moonbeams | The Blessed Madonna | WEA/Warner | 120 | 2 |
| 23 | Frequency | Pixie Lane And Kazi Flip feat. Rosanne Hamilton | SeraWise/DRM | 118 | 2 |
| 24 | Leave Me Like This | Skrillex And Bobby Raps | OWSLA/Atlantic/Warner | 106 | 2 |
| 25 | B.O.T.A. (Baddest Of Them All) | Eliza Rose And Interplanetary Criminal | OneHouseX/Warner | 98 | 2 |
| 26 | Miss You | southstar | B1/Columbia/SonyMusic | 98 | 2 |
| 27 | Down The Line | Alison Wonderland | EMI/Universal | 96 | 2 |
| 28 | Takeover (Dick Johnson Remix) | Lee Mvtthews feat. NÜ | LeeMvtthews/DRM | 90 | 1 |
| 29 | Beat Goes On (Rhythm To The Brain) | Campbell | Atlantic/Warner | 84 | 1 |
| 30 | Better Than Gold | Justin Hawkes feat. Andrew Hellier | Pilot./AEI | 84 | 2 |
| 31 | messy in heaven | venbee And goddard. | Columbia/SonyMusic | 80 | 2 |
| 32 | Off The Ground | Sub Focus | EMI/Universal | 80 | 2 |
| 33 | Bel Mercy | Jengi | FFRR/Warner | 78 | 1 |
| 34 | Fever Dreamer | SG Lewis feat. Charlotte Day Wilson And Channel Tres | EMI/Universal | 78 | 1 |
| 35 | Ready To Fly | Sub Focus And Dimension | EMI/Universal | 78 | 2 |
| 36 | Summer Time (Flowidus 2021 Remix) | Tiki Taane | DirtyDub/Rhythm/DRM | 78 | 1 |
| 37 | Bad Memories | MEDUZA And James Carter feat. Elley Duhé And FAST BOY | Island/Universal | 76 | 2 |
| 38 | Yeah The Girls | Fisher feat. MERYLL | EtcEtc/TheOrchard | 76 | 2 |
| 39 | Unholy (Disclosure Remix) | Sam Smith And Kim Petras | EMI/Universal | 66 | 1 |
| 40 | JOY (God Only Knows) | Joy Anonymous | Island/Universal | 60 | 1 |