| 1 | On My Mind | Mashd N Kutcher | Neon/Universal | 212 | 2 |
| 2 | California Dreamin' | Chris Lorenzo feat. High Jinx | AstralWerks/Universal | 208 | 2 |
| 3 | Infinite (Freedom) | K Motionz | SleeplessMusic/Believe | 202 | 2 |
| 4 | Do It To It | ACRAZE feat. Cherish | ThriveMusic/Universal | 194 | 3 |
| 5 | Run To The Unknown | Sly Chaos feat. Matisse | SlyChaos/DRM | 194 | 2 |
| 6 | Used To This | Wilkinson And Issey Cross | SleeplessMusic/Warner | 190 | 2 |
| 7 | Human | John Summit feat. Echoes | FFRR/Warner | 186 | 2 |
| 8 | Down Under | Luude feat. Colin Hay | SweatItOut/CentralStation/Xelon | 180 | 2 |
| 9 | Somebody To Love | Ben Kim | Realm/Warner | 174 | 1 |
| 10 | Last Time | Subsonic | Elevate/Believe | 168 | 2 |
| 11 | Summer Time (Flowidus 2021 Remix) | Tiki Taane | DirtyDub/Rhythm/DRM | 168 | 1 |
| 12 | Breathe | Samson Live | SamsonLive/Xelon | 156 | 1 |
| 13 | Love Can't Turn Around | Pete Tong, Riton And Vula feat. The Heritage Orchestra And Jules Buckley | MOS/SonyMusic | 148 | 2 |
| 14 | Easy On Me (Sigma Remix) | Adele | Columbia/SonyMusic | 144 | 2 |
| 15 | Hold You | Audioscribe | SleeplessMusic/Believe | 144 | 1 |
| 16 | Wait A Minute | Biscits | Solotoko/Warner | 132 | 1 |
| 17 | Freedom | Bru-C | Bru-CMusic/Rhythm | 126 | 1 |
| 18 | Deep End (Hybrid Minds Remix) | Birdy | Atlantic/Warner | 116 | 2 |
| 19 | Don't You Want Me (Purple Disco Machine Remix) | The Human League | Virgin/Universal | 114 | 1 |
| 20 | Intimidated | Kaytranada feat. H.E.R. | Kaytranada/RCA/SonyMusic | 114 | 1 |
| 21 | Loved Up | Kings feat. Haan808 | ArchAngel/DRM | 114 | 1 |
| 22 | Groovejet (If This Ain't Love) (Purple Disco Machine & Lorenz Rhode Remix) | Spiller feat. Sophie Ellis-Bextor | Defected/Warner | 108 | 1 |
| 23 | INDUSTRY BABY (Fat Tony Remix) | Lil Nas X feat. Jack Harlow | Columbia/SonyMusic/Warner | 108 | 1 |
| 24 | Peace (Dick Johnson Remix) | Sweet Mix Kids feat. Hawkins | SweetMixKids/DRM | 102 | 1 |
| 25 | I Wish | Joel Corry feat. Mabel | Atlantic/Warner | 96 | 2 |
| 26 | Straight Up Relaxin' | Yung Bae feat. Cosmo's Midnight | Arista/SonyMusic | 96 | 1 |
| 27 | Faded | Sigma, LOWES And U137 | 3Beat/PM:AM/Universal | 90 | 1 |
| 28 | Remember (TCTS Remix) | Becky Hill And David Guetta | Polydor/Universal | 90 | 1 |
| 29 | Streetside | Bru-C And Bou | Crucast | 84 | 1 |
| 30 | Ain't No Sunshine | Dubdogz And JØRD feat. Jasmine Pace | Spinnin'/Warner | 78 | 1 |
| 31 | Cold Heart (Claptone Remix) | Elton John And Dua Lipa | EMI/Universal | 78 | 1 |
| 32 | Love Tonight | Shouse | HellBeach | 74 | 2 |
| 33 | Burning Cold | Witters | Lunchbox | 72 | 1 |
| 34 | Takeover | Lee Mvtthews feat. NÜ | LeeMvtthews/DRM | 62 | 2 |
| 35 | Dreams | Gorgon City And Jem Cooke | Positiva/Universal | 60 | 1 |
| 36 | Hope | Sigma And Carla Marie | 3Beat/PM:AM/Universal | 60 | 1 |
| 37 | Ritual (Under Your Spell) | Shapeshifter | A.R.T./Universal | 60 | 1 |
| 38 | Want Need Love (Dimension Remix) | Prospa | Polydor/Universal | 60 | 1 |
| 39 | Just Feels Tight | Fisher | EtcEtc/TheOrchard | 56 | 2 |
| 40 | Fireworks | Purple Disco Machine feat. Moss Kena And The Knocks | SweatItOut/Warner | 54 | 1 |